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Patterned Electrospun Nanofiber Matrices Via Localized Dissolution: Potential for Guided Tissue Formation
Author(s) -
Jia Chao,
Yu Dou,
Lamarre Marven,
Leopold Philip L.,
Teng Yang D.,
Wang Hongjun
Publication year - 2014
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201403509
Subject(s) - nanofiber , materials science , dissolution , electrospinning , nanotechnology , layer (electronics) , tissue engineering , 3d printing , inkwell , chemical engineering , biomedical engineering , composite material , polymer , medicine , engineering
With the assistance of an ink‐jet printer , solvent (the “ink”) can be controllably and reproducibly printed onto electrospun nanofiber meshes (the “paper”) to generate various micropatterns and subsequently guide distinct cellular organization and phenotype expression. In combination with the nanofiber‐assisted layer‐by‐layer cell assembly, the patterned electrospun meshes will define an instructive microenvironment for guided tissue formation.