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Perylene‐Diimide‐Based Nanoparticles as Highly Efficient Photoacoustic Agents for Deep Brain Tumor Imaging in Living Mice
Author(s) -
Fan Quli,
Cheng Kai,
Yang Zhen,
Zhang Ruiping,
Yang Min,
Hu Xiang,
Ma Xiaowei,
Bu Lihong,
Lu Xiaomei,
Xiong Xiaoxing,
Huang Wei,
Zhao Heng,
Cheng Zhen
Publication year - 2015
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201402972
Subject(s) - perylene , photoacoustic imaging in biomedicine , materials science , diimide , nanoparticle , molecular imaging , nanotechnology , fluorescence , in vivo , optics , biology , physics , microbiology and biotechnology
In order to promote preclinical and clinical applications of photoacoustic imaging, novel photoacoustic contrast agents are highly desired for molecular imaging of diseases, especially for deep tumor imaging. Here, perylene‐3,4,9,10‐tetracarboxylic diiimide‐based near‐infrared‐absorptive organic nanoparticles are reported as an effi cient agent for photoacoustic imaging of deep brain tumors in living mice with enhanced permeability and retention effect.