Premium
Gd‐Encapsulated Carbonaceous Dots with Efficient Renal Clearance for Magnetic Resonance Imaging
Author(s) -
Chen Hongmin,
Wang Geoffrey D.,
Tang Wei,
Todd Trever,
Zhen Zipeng,
Tsang Chu,
Hekmatyar Khan,
Cowger Taku,
Hubbard Richard B.,
Zhang Weizhong,
Stickney John,
Shen Baozhong,
Xie Jin
Publication year - 2014
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201402964
Subject(s) - materials science , magnetic resonance imaging , fluorescence , nuclear magnetic resonance , nanotechnology , optical imaging , biomedical engineering , optics , medicine , radiology , physics
Nanoprobes for MRI and optical imaging are demonstrated. Gd@C‐dots possess strong fluorescence and can effectively enhance signals on T 1 ‐weighted MR images. The nanoprobes have low toxicity, and, despite a relatively large size, can be efficiently excreted by renal clearance from the host after systemic injection.