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Amphiphilic Star Copolymer‐Based Bimodal Fluorogenic/Magnetic Resonance Probes for Concomitant Bacteria Detection and Inhibition
Author(s) -
Li Yamin,
Yu Hansen,
Qian Yinfeng,
Hu Jinming,
Liu Shiyong
Publication year - 2014
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201402797
Subject(s) - amphiphile , copolymer , cationic polymerization , materials science , star (game theory) , covalent bond , bacteria , aqueous solution , nuclear magnetic resonance , polymer chemistry , organic chemistry , chemistry , polymer , biology , physics , composite material , genetics , astrophysics
Four‐arm star‐shaped copolymers , TPE‐ star ‐P(DMA‐ co ‐BMA‐ co ‐ Gd ), containing TPE cores with an aggregation‐induced emission (AIE) feature, a T 1 ‐type magnetic resonance (MR) contrast agent, and amphiphilic cationic arms, are synthesized. By taking advantage of non‐covalent interactions between star copolymers and bacteria surfaces, bimodal fluorometric/MR detection and concomitant inhibition of both Gram‐positive and Gram‐negative bacteria strains in aqueous media are explored.