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A Smart “Sense‐Act‐Treat” System: Combining a Ratiometric pH Sensor with a Near Infrared Therapeutic Gold Nanocage
Author(s) -
Shi Peng,
Liu Zhen,
Dong Kai,
Ju Enguo,
Ren Jinsong,
Du Yingda,
Li Zhengqiang,
Qu Xiaogang
Publication year - 2014
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201402522
Subject(s) - nanocages , materials science , sense (electronics) , nanotechnology , infrared , fluorescence , catalysis , electrical engineering , optics , chemistry , biochemistry , physics , engineering
Herein, we design a “sense‐act‐treat” system via the combination of a ratiometric pH sensor with a therapeutic gold nanocage. Our design could “sense” the tumor through two‐state switching of fluorescence and further provide chemotherapy and hyperthermia for “treating” the tumor, showing the potential for future biomedical applications.