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Switchable Water‐Adhesive, Superhydrophobic Palladium‐Layered Silicon Nanowires Potentiate the Angiogenic Efficacy of Human Stem Cell Spheroids
Author(s) -
Seo Jungmok,
Lee Jung Seung,
Lee Kihong,
Kim Dayeong,
Yang Kisuk,
Shin Sera,
Mahata Chandreswar,
Jung Hwae Bong,
Lee Wooyoung,
Cho SeungWoo,
Lee Taeyoon
Publication year - 2014
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201402273
Subject(s) - spheroid , materials science , nanotechnology , silicon nanowires , cell , adhesive , nanowire , biophysics , layer (electronics) , cell culture , chemistry , biology , biochemistry , genetics
A switchable water‐adhesive, super­hydrophobic nanowire surface is developed for the formation of functional stem cell spheroids. The sizes of hADSC spheroids are readily controllable on the surface. Our surface increases cell‐cell and cell‐matrix interaction, which improves viability and paracrine secretion of the spheroids. Accordingly, the hADSC spheroids produced on the surface exhibit significantly enhanced angiogenic efficacy.

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