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Cationic Conjugated Polymers for Discrimination of Microbial Pathogens
Author(s) -
Yuan Huanxiang,
Liu Zhang,
Liu Libing,
Lv Fengting,
Wang Yilin,
Wang Shu
Publication year - 2014
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201400636
Subject(s) - cationic polymerization , conjugated system , materials science , polymer , bacteria , phenylene , molecule , polymer chemistry , organic chemistry , chemistry , biology , composite material , genetics
A new cationic poly(phenylene vinylene) derivative (PPV‐NMe 3 + ) is synthesized, and it exhibits a differential binding ability to microbial cell walls with different components. By varying the ion strengths of the buffer solution, single PPV‐NMe 3 + molecules can discriminate fungi, Gram‐positive bacteria, and Gram‐negative bacteria in a rapid and simple manner. Thus, cationic conjugated polymers exhibit high potential as a diagnostic material for the detection and discrimination of pathogens.