A Novel Poly(amido amine)‐Dendrimer‐Based Hydrogel as a Mimic for the Extracellular Matrix | Zendy

Wang Yao | Zendy; Zhao Qiang | Zendy; Zhang He | Zendy; Yang Sheng | Zendy; Jia Xinru | Zendy

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A Novel Poly(amido amine)‐Dendrimer‐Based Hydrogel as a Mimic for the Extracellular Matrix

Author(s) -

Wang Yao,

Zhao Qiang,

Zhang He,

Yang Sheng,

Jia Xinru

Publication year - 2014

Publication title -

advanced materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.707

H-Index - 527

eISSN - 1521-4095

pISSN - 0935-9648

DOI - 10.1002/adma.201400323

Subject(s) - dendrimer , extracellular matrix , materials science , self healing hydrogels , tissue engineering , drug delivery , nanotechnology , computer science , biomedical engineering , polymer chemistry , microbiology and biotechnology , biology , engineering

The extracellular matrix is mimicked by a novel dendrimer‐based hydrogel, which exhibits a highly interconnected porous network, enhanced mechanical stiffness, and a low swelling ratio. The hydrogel system supports the proliferation and differentiation of mesenchymal stem cells without any cytotoxic effects. This dendrimer‐based hydrogel may serve as a model for developing new advanced materials with applications in tissue engineering.

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