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Bionanotechnology: Axonal Alignment and Enhanced Neuronal Differentiation of Neural Stem Cells on Graphene‐Nanoparticle Hybrid Structures (Adv. Mater. 38/2013)
Author(s) -
Solanki Aniruddh,
Chueng SyTsong Dean,
Yin Perry T.,
Kappera Rajesh,
Chhowalla Manish,
Lee KiBum
Publication year - 2013
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201370243
Subject(s) - materials science , neural stem cell , graphene , nanobiotechnology , nanotechnology , nanoparticle , stem cell , microbiology and biotechnology , biology
Graphene‐nanoparticle hybrid structures have been developed to control the behavior of human neural stem cells (hNSCs) in a unique manner. The axons from the differentiated hNSCs, as described by Ki‐Bum Lee and co‐workers on page 5477 , show enhanced growth and alignment. While the axonal alignment is primarily due to the presence of graphene, the underlying nanoparticle monolayer causes enhanced neuronal differentiation of the hNSCs, thus having great implications of these hybrid‐nanostructures for neuroregenerative medicine.