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Microencapsulation: Microencapsulation of Chemotherapeutics into Monodisperse and Tunable Biodegradable Polymers via Electrified Liquid Jets: Control of Size, Shape, and Drug Release (Adv. Mater. 33/2013)
Author(s) -
Fattahi Pouria,
Borhan Ali,
Abidian Mohammad Reza
Publication year - 2013
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201370205
Subject(s) - materials science , dispersity , biodegradable polymer , polymer , capillary action , drug delivery , nanotechnology , chemical engineering , polymer chemistry , composite material , engineering
On page 4555 , Mohammad Reza Abidian and co‐workers describe the use of an electrojetting technique, whereby a conducting liquid is injected at a constant flow rate through a high‐voltage electrified capillary tube, for the microencapsulation of the antitumor agent 1,3‐bis(2‐chloroethyl)‐1‐nitrosourea into biodegradable polymer poly(lactic‐co‐glycolic acid). The technique results in microcapsules having high drug encapsulation efficiency, tunable drug loading capacity, and narrow size distribution.