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Sensors: Fluorogenic Probing of Specific Recognitions between Sugar Ligands and Glycoprotein Receptors on Cancer Cells by an Economic Graphene Nanocomposite (Adv. Mater. 30/2013)
Author(s) -
Zhang HaiLin,
Wei XiaoLi,
Zang Yi,
Cao JiaYi,
Liu Shanshan,
He XiaoPeng,
Chen Qibin,
Long YiTao,
Li Jia,
Chen GuoRong,
Chen Kaixian
Publication year - 2013
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201370190
Subject(s) - graphene , materials science , nanotechnology , receptor , glycomics , glycoprotein , transmembrane protein , nanomaterials , stacking , cancer cell , biophysics , biochemistry , biology , cancer , chemistry , glycan , organic chemistry , genetics
Ingenious detection of the universal sugar‐protein interactions at a cellular level has long remained a formidable task, hampering the advancement of Glycomics. Guo‐Rong Chen, Jia Li, Xiao‐Peng He and co‐workers devise an economic system in work described on page 4097 . The work involves simply stacking glycosyl rhodamines to graphene oxide for the generation of a fluorogenic sugary nanomaterial suited for probing transmembrane glycoprotein receptors that are uniquely pervaded on cancer cells in situ.