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Self‐Assembly: A Robust Route to Enzymatically Functional, Hierarchically Self‐Assembled Peptide Frameworks (Adv. Mater. 19/2013)
Author(s) -
Sangiambut S.,
Chan K.,
Thomson N. M.,
Sato S.,
Tsuge T.,
Doi Y.,
Sivaniah E.
Publication year - 2013
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201370121
Subject(s) - nanofiber , peptide , materials science , biocompatible material , self assembly , self assembling peptide , nanotechnology , covalent bond , polymerization , immobilized enzyme , enzyme , biophysics , biochemistry , biomedical engineering , organic chemistry , polymer , chemistry , composite material , biology , medicine
Adding enzyme biofunctionality to peptide nanofibers is challenging since this can inhibit enzyme activity and peptide self‐assembly. Easan Sivaniah and co‐workers demonstrate on page 2661 the attachment of a polymerization synthase to peptide nanofibers via a selective non‐covalent peptide tag. The biofunctionalization, rapidly achieved, generates a biocompatible biopolyester coat on the fibers, with applicability in biomedical engineering. Cover image by Effigos AG.