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Controlled‐Release Systems for Metal‐Based Nanomedicine: Encapsulated/Self‐Assembled Nanoparticles of Anticancer Gold(III)/Platinum(II) Complexes and Antimicrobial Silver Nanoparticles
Author(s) -
Lok ChunNam,
Zou Taotao,
Zhang JingJing,
Lin Iris WingShan,
Che ChiMing
Publication year - 2014
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201305617
Subject(s) - nanomedicine , nanotechnology , materials science , antimicrobial , nanomaterials , platinum , nanoparticle , combinatorial chemistry , silver nanoparticle , metal , chemistry , organic chemistry , catalysis , metallurgy
The therapeutic applications of many anticancer or antimicrobial metal complexes often suffer from low solubility and low stability in physiological conditions or from drug resistance. To circumvent these problems, nanoparticle systems that allow controlled release and specific accumulation in the targeted disease tissue are of advantage for efficient treatment with minimal toxicity. The focus of this Research News is metal‐based nanomaterials comprising anticancer gold(III)/platinum(II) complexes or antimicrobial silver, highlighting the controlled‐release properties of self‐assembled metal systems.