Premium
Drug Delivery with PEGylated MoS 2 Nano‐sheets for Combined Photothermal and Chemotherapy of Cancer
Author(s) -
Liu Teng,
Wang Chao,
Gu Xing,
Gong Hua,
Cheng Liang,
Shi Xiaoze,
Feng Liangzhu,
Sun Baoquan,
Liu Zhuang
Publication year - 2014
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201305256
Subject(s) - drug delivery , photothermal therapy , materials science , nanotechnology , drug , ethylene glycol , anticancer drug , nano , doxorubicin , cancer treatment , cancer , chemotherapy , pharmacology , medicine , organic chemistry , chemistry , surgery , composite material
MoS 2 nanosheets functionalized with polyethylene glycol are for the first time used as a multifunctional drug delivery system with high drug loading capacities. Using doxorubicin as the model drug and taking advantages of the strong near‐infrared absorbance of MoS 2 , combined photothermal and chemotherapy of cancer is realized in animal experiments, achieving excellent synergistic anti‐tumor effect upon systemic administration.