Proteoglycans and Glycosaminoglycans Improve Toughness of Biocompatible Double Network Hydrogels | Zendy

Zhao Yu | Zendy; Nakajima Tasuku | Zendy; Yang Jing Jing | Zendy; Kurokawa Takayuki | Zendy; Liu Jian | Zendy; Lu Jishun | Zendy; Mizumoto Shuji | Zendy; Sugahara Kazuyuki | Zendy; Kitamura Nobuto | Zendy; Yasuda Kazunori | Zendy; Daniels A. U. D. | Zendy; Gong Jian Ping | Zendy

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Proteoglycans and Glycosaminoglycans Improve Toughness of Biocompatible Double Network Hydrogels

Author(s) -

Zhao Yu,

Nakajima Tasuku,

Yang Jing Jing,

Kurokawa Takayuki,

Liu Jian,

Lu Jishun,

Mizumoto Shuji,

Sugahara Kazuyuki,

Kitamura Nobuto,

Yasuda Kazunori,

Daniels A. U. D.,

Gong Jian Ping

Publication year - 2014

Publication title -

advanced materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.707

H-Index - 527

eISSN - 1521-4095

pISSN - 0935-9648

DOI - 10.1002/adma.201303387

Subject(s) - self healing hydrogels , materials science , biocompatible material , chondroitin sulfate , biopolymer , hyaluronic acid , glycosaminoglycan , polymer , polypyrrole , toughness , chemical engineering , nanotechnology , polymer science , biomedical engineering , polymer chemistry , composite material , chemistry , biochemistry , polymerization , anatomy , medicine , engineering

Based on the molecular stent concept , a series of tough double‐network hydrogels (St‐DN gels) made from the components of proteoglycan aggregates – chondroitin sulfate proteoglycans (1), chondroitin sulfate (2), and sodium hyaluronate (3) – are successfully developed in combination with a neutral biocompatible polymer. This work demonstrates a promising method to create biopolymer‐based tough hydrogels for biomedical applications.

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