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Carbon Nanodots Featuring Efficient FRET for Real‐Time Monitoring of Drug Delivery and Two‐Photon Imaging
Author(s) -
Tang Jing,
Kong Biao,
Wu Hao,
Xu Ming,
Wang Yongcheng,
Wang Yanli,
Zhao Dongyuan,
Zheng Gengfeng
Publication year - 2013
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201303124
Subject(s) - förster resonance energy transfer , drug delivery , nanotechnology , nanodot , materials science , fluorescence , biocompatibility , computer science , physics , optics , metallurgy
A FRET‐based carbon nanodot (CDot) drug delivery platform has been developed. These CDots offer excellent biocompatibility, stable fluorescence, and efficient FRET between CDots and the attached fluorescent drug molecules, such as doxorubicin, enabling enhanced drug delivery, convenient cell imaging, and real‐time monitoring of drug release. Moreover, the FRET‐based two‐photon imaging and drug tracking in deep tissues are also demonstrated.