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Fluorescent Multiblock π‐Conjugated Polymer Nanoparticles for In Vivo Tumor Targeting
Author(s) -
Ahmed Eilaf,
Morton Stephen W.,
Hammond Paula T.,
Swager Timothy M.
Publication year - 2013
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201301656
Subject(s) - conjugated system , in vivo , materials science , fluorescence , nanoparticle , nanotechnology , polymer , surface modification , biophysics , folic acid , chemistry , biology , medicine , physics , microbiology and biotechnology , quantum mechanics , composite material
Highly fluorescent multiblock conjugated polymer nanoparticles with folic acid surface ligands are highly effective for bioimaging and in vivo tumor targeting. The targeted nanoparticles were preferentially localized in tumor cells in vivo, thereby illustrating their potential for diagnostic and therapeutic applications.