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Label‐Free Polypeptide‐Based Enzyme Detection Using a Graphene‐Nanoparticle Hybrid Sensor (Adv. Mater. 45/2012)
Author(s) -
Myung Sung,
Yin Perry T.,
Kim Cheoljin,
Park Jaesung,
Solanki Aniruddh,
Reyes Pavel Ivanoff,
Lu Yicheng,
Kim Kwang S.,
Lee KiBum
Publication year - 2012
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201290274
Subject(s) - biosensor , materials science , graphene , nanoparticle , linker , nanotechnology , hysteresis , enzyme , peptide , organic chemistry , biochemistry , computer science , chemistry , physics , quantum mechanics , operating system
A novel approach for the detection of enzymes using a graphene–nanoparticle (NP) hybrid biosensor is developed by Ki‐Bum Lee and co‐workers on page 6081 . This biosensor can detect the activity of an enzyme and determine its concentration by measuring the change in electrical hysteresis that results from the dynamic interaction of the target enzyme with its corresponding peptide linker resulting in the release of nanoparticles.