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Functional Nanovehicles: Molecular Engineered Super‐Nanodevices: Smart and Safe Delivery of Potent Drugs into Tumors (Adv. Mater. 27/2012)
Author(s) -
Ding Mingming,
Li Jiehua,
He Xueling,
Song Nijia,
Tan Hong,
Zhang Yi,
Zhou Lijuan,
Gu Qun,
Deng Hua,
Fu Qiang
Publication year - 2012
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201290165
Subject(s) - nanodevice , materials science , drug delivery , in vivo , nanotechnology , drug , pharmacology , medicine , biology , microbiology and biotechnology
A molecularly engineered super‐nanodevice integrates various desired properties in a smart and co‐ordinated way, allowing certain functionalities to be switched on or off as required. As shown on page 3639 by H. Tan, Q. Fu, and co‐workers, this nanovehicle could break through complex physiological barriers, and then precisely ferry potent toxic drugs into tumor cells in vivo, thus significantly maximizing the therapeutic efficacy and reducing drug toxicity.