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DNA Hybridization: Direct Attachment of Microbial Organisms to Material Surfaces Through Sequence‐Specific DNA Hybridization (Adv. Mater. 18/2012)
Author(s) -
Twite Amy A.,
Hsiao Sonny C.,
Onoe Hiroaki,
Mathies Richard A.,
Francis Matthew B.
Publication year - 2012
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201290104
Subject(s) - azotobacter vinelandii , dna , dna–dna hybridization , saccharomyces cerevisiae , biology , sequence (biology) , dna sequencing , nucleic acid thermodynamics , computational biology , biochemistry , biophysics , materials science , genetics , nanotechnology , bacteria , base sequence , gene , nitrogenase , nitrogen fixation
M. B. Francis and co‐workers develop a new chemical method for the attachment of single‐stranded DNA molecules to the surfaces of these organisms. On page 2380 , they describe how, when exposed to substrates bearing the sequence complements, the microbes can be attached to specified locations with very high efficiency. The use of multiple DNA sequences allows complex microbial ‘communities’ to be generated, potentially allowing the study of symbiotic relationships. Shown are Synechocystis (red), Saccharomyces cerevisiae (green), and Azotobacter vinelandii (blue).