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Tissue Engineering: Osteophilic Multilayer Coatings for Accelerated Bone Tissue Growth (Adv. Mater. 11/2012)
Author(s) -
Shah Nisarg J.,
Hong Jinkee,
Hyder Md. Nasim,
Hammond Paula T.
Publication year - 2012
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201290062
Subject(s) - materials science , biomedical engineering , bone tissue , osteoblast , tissue engineering , bone growth , bone formation , implant , nanotechnology , in vitro , surgery , biology , biochemistry , medicine , endocrinology
The development of stable skeletal joint prostheses ‐ con‐formal, nanoscale electrostatic coatings capable of de novo bone regeneration ‐ is reported by P. T. Hammond and co‐workers on page 1445 . These coatings contain a combination of hydroxyapatite and bone growth factor, components which are present in and which regulate the structure of the bone. Osteoblast cells adhere to these coatings and lay down new bone on and around the implant for stable bonding with the surrounding bone tissue.