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Large‐Scale, Ultrapliable, and Free‐Standing Nanomembranes
Author(s) -
Kang Edward,
Ryoo Jihee,
Jeong Gi Seok,
Choi Yoon Young,
Jeong Seung Min,
Ju Jongil,
Chung Seok,
Takayama Shuichi,
Lee SangHoon
Publication year - 2013
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201204619
Subject(s) - materials science , monolayer , membrane , nanotechnology , computer science , biology , genetics
The creation and characterization of large‐area ultrathin highly pliable free‐standing PDMS membranes and their application to the study of cellular epithelia is described. The ultra‐thin membranes permitted the straight forward calculation of cell monolayer moduli, derived from measured stress–strain curves. These measurements allowed the unprecedented detection of cellular‐level injury in the epithelia caused by the rupture of cell–cell tight junctions in response to stretching.