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Triggering Cell Adhesion, Migration or Shape Change with a Dynamic Surface Coating
Author(s) -
van Dongen Stijn F. M.,
Maiuri Paolo,
Marie Emmanuelle,
Tribet Christophe,
Piel Matthieu
Publication year - 2013
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201204474
Subject(s) - materials science , adhesion , coating , surface (topology) , shape change , composite material , nanotechnology , cell adhesion , biophysics , geometry , biology , mathematics
There's an APP for that: cell‐repellent APP (azido‐[polylysine‐g‐PEG]) is used to create substrates for spatially controlled dynamic cell adhesion. The simple addition of a functional peptide to the culture medium rapidly triggers cell adhesion. This highly accessible yet powerful technique allows diverse applications, demonstrated through tissue motility assays, patterned coculturing and triggered cell shape change.