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Hydrophobic Interaction‐Mediated Capture and Release of Cancer Cells on Thermoresponsive Nanostructured Surfaces
Author(s) -
Liu Hongliang,
Liu Xueli,
Meng Jingxin,
Zhang Pengchao,
Yang Gao,
Su Bin,
Sun Kang,
Chen Li,
Han Dong,
Wang Shutao,
Jiang Lei
Publication year - 2013
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201203826
Subject(s) - materials science , cancer cell , hydrophobic effect , nanotechnology , cancer , biophysics , chemistry , biochemistry , biology , genetics
Capture and release of cancer cells: a thermoresponsive nanostructured surface is designed to reversibly capture and release cancer cells, wherein hydrophobic interaction helps the realization of target capture/release of cancer cells. The unique nature of the designed platform is based on the synergistic effect of hydrophobic interactions between the smart surface and the hydrophobic anchor (i.e., biotin‐BSA), and topographic interactions between the nanostructured substrates and cancer cells.