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Functionalizing Calcium Phosphate Biomaterials with Antibacterial Silver Particles
Author(s) -
Lee Jae Sung,
Murphy William L.
Publication year - 2013
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201203370
Subject(s) - library science , engine department , rehabilitation engineering , engineering , medicine , rehabilitation , computer science , engineering management , physical therapy
Antimicrobial silver particles are created on calcium phosphate (CaP) biomaterials by sequentially incubating in citric acid and silver nitrate solutions . The subsequent silver release kinetics and released dosage are controlled by simply changing the solution conditions during growth of silver particles. Released silver efficiently suppresses the growth of gram‐positive Staphylococcus aureus and gram‐negative Escherichia coli without significant cytotoxicity to eukaryotic cells.