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A Synergistically Enhanced T 1 – T 2 Dual‐Modal Contrast Agent
Author(s) -
Zhou Zijian,
Huang Dengtong,
Bao Jianfeng,
Chen Qiaoli,
Liu Gang,
Chen Zhong,
Chen Xiaoyuan,
Gao Jinhao
Publication year - 2012
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201203169
Subject(s) - materials science , dispersity , nanoparticle , contrast (vision) , nanotechnology , magnetic field , iron oxide nanoparticles , nuclear magnetic resonance , optics , polymer chemistry , physics , quantum mechanics
Monodisperse Gd 2 O 3 ‐embedded iron oxide (GdIO) nanoparticles can simultaneously enhance the local magnetic field intensities of each other under an external magnetic field and result in synergistic enhancement of T 1 and T 2 effects. GdIO nanoparticles have the unique property to be both T 1 and T 2 contrast agents and can potentially lead to higher accuracy in cancer diagnosis, particularly liver tumors.