Unraveling Stress‐Induced Toxicity Properties of Graphene Oxide and the Underlying Mechanism | Zendy

Zhang Wendi | Zendy; Wang Chi | Zendy; Li Zhongjun | Zendy; Lu Zhenzhen | Zendy; Li Yiye | Zendy; Yin JunJie | Zendy; Zhou YuTing | Zendy; Gao Xingfa | Zendy; Fang Ying | Zendy; Nie Guangjun | Zendy; Zhao Yuliang | Zendy

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Unraveling Stress‐Induced Toxicity Properties of Graphene Oxide and the Underlying Mechanism

Author(s) -

Zhang Wendi,

Wang Chi,

Li Zhongjun,

Lu Zhenzhen,

Li Yiye,

Yin JunJie,

Zhou YuTing,

Gao Xingfa,

Fang Ying,

Nie Guangjun,

Zhao Yuliang

Publication year - 2012

Publication title -

advanced materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.707

H-Index - 527

eISSN - 1521-4095

pISSN - 0935-9648

DOI - 10.1002/adma.201202678

Subject(s) - graphene , oxidizing agent , materials science , radical , mechanism (biology) , oxide , toxicity , biophysics , nanotechnology , chemistry , biochemistry , organic chemistry , biology , metallurgy , philosophy , epistemology

Graphene oxide shows stress‐induced toxicity properties in vivo under different pathophysiological conditions. A dual‐path chemical mechanism, involving the overproduction of hydroxyl radicals and the formation of oxidizing cytochrome c intermediates, is responsible for the toxicity properties.

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