A Hydrogen Peroxide‐Responsive O 2  Nanogenerator for Ultrasound and Magnetic‐Resonance Dual Modality Imaging | Zendy

Yang Fang | Zendy; Hu Sunling | Zendy; Zhang Yu | Zendy; Cai Xiaowei | Zendy; Huang Yan | Zendy; Wang Feng | Zendy; Wen Song | Zendy; Teng Gaojun | Zendy; Gu Ning | Zendy

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A Hydrogen Peroxide‐Responsive O 2 Nanogenerator for Ultrasound and Magnetic‐Resonance Dual Modality Imaging

Author(s) -

Yang Fang,

Hu Sunling,

Zhang Yu,

Cai Xiaowei,

Huang Yan,

Wang Feng,

Wen Song,

Teng Gaojun,

Gu Ning

Publication year - 2012

Publication title -

advanced materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.707

H-Index - 527

eISSN - 1521-4095

pISSN - 0935-9648

DOI - 10.1002/adma.201202367

Subject(s) - prussian blue , modality (human–computer interaction) , hydrogen peroxide , magnetic resonance imaging , materials science , proton magnetic resonance , nanoparticle , ultrasound , in vivo , nuclear magnetic resonance , nanotechnology , combinatorial chemistry , computer science , chemistry , electrochemistry , radiology , physics , organic chemistry , artificial intelligence , medicine , electrode , microbiology and biotechnology , biology

It is found that Prussian Blue nanoparticles (PBNPs) possess a catalase‐like activity to catalyse the breakdown of H 2 O 2 into oxygen (O 2 ) molecules under the neutral conditions (pH = 7.4). Based on this finding, we have developed a new strategy in which PBNPs can be excellent ultrasound (US) and magnetic‐resonance (MR) dual modality imaging contrast agents for H 2 O 2 diagnostics in vitro and in vivo.

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