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Molecular Catch and Release: Controlled Delivery Using Optical Trapping with Light‐Responsive Liposomes
Author(s) -
Leung Sarah J.,
Romanowski Marek
Publication year - 2012
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201202180
Subject(s) - materials science , optical tweezers , liposome , nanocapsules , nanotechnology , payload (computing) , trapping , dispersity , biophysics , surface plasmon resonance , nanoparticle , optics , biology , computer network , ecology , physics , network packet , computer science , polymer chemistry
Gold‐coated liposomes are maneuvered using an optical trap to achieve precise delivery of encapsulated molecular cargo. Movement and payload release from these plasmon resonant nanocapsules are independently controlled using a pulsed trapping beam. This technology enables in vitro delivery of a payload to a selected cell and may be applied to the interrogation of individual cells within their biological microenvironment.