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Microfluidic Spinning of Flat Alginate Fibers with Grooves for Cell‐Aligning Scaffolds
Author(s) -
Kang Edward,
Choi Yoon Young,
Chae SuKyoung,
Moon JinHee,
Chang JoonYoung,
Lee SangHoon
Publication year - 2012
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201201232
Subject(s) - materials science , spinning , microfluidics , tissue engineering , nanotechnology , composite material , biomedical engineering , medicine
Alginate microribbons with longitudinally grooved microstructures are continuously fabricated by means of a microfluidic system. The number and dimensions of the microgroovesare successfully controlled by regulation of the slit‐shaped channel (yellow in figure). This method opens up the possibility of mass production of scaffolds for tissue engineering purposes, as it is proved that the grooved flat fibers can be used to align other types of cells in culture.