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Generation of a Library of Non‐Toxic Quantum Dots for Cellular Imaging and siRNA Delivery
Author(s) -
Subramaniam Prasad,
Lee Seung Jae,
Shah Shreyas,
Patel Sahishnu,
Starovoytov Valentin,
Lee KiBum
Publication year - 2012
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201201019
Subject(s) - quantum dot , nanotechnology , materials science , biocompatible material , cytotoxicity , gene delivery , biomedical engineering , chemistry , transfection , gene , biochemistry , medicine , in vitro
The development of non‐toxic quantum dots and further investigation of their composition‐dependent cytotoxicity in a high‐throughput manner have been critical challenges for biomedical imaging and gene delivery. Herein, we report a rapid sonochemical synthetic methodology for generating a library of highly biocompatible ZnS‐AgInS 2 (ZAIS) quantum dots for cellular imaging and siRNA delivery.