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Bioactive Hydrogels: Maleimide Cross‐Linked Bioactive PEG Hydrogel Exhibits Improved Reaction Kinetics and Cross‐Linking for Cell Encapsulation and In Situ Delivery (Adv. Mater. 1/2012)
Author(s) -
Phelps Edward A.,
Enemchukwu Nduka O.,
Fiore Vincent F.,
Sy Jay C.,
Murthy Niren,
Sulchek Todd A.,
Barker Thomas H.,
García Andrés J.
Publication year - 2012
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201190203
Subject(s) - maleimide , materials science , cell encapsulation , self healing hydrogels , in situ , polyethylene glycol , peg ratio , tissue engineering , kinetics , polymer chemistry , chemical engineering , nanotechnology , biomedical engineering , organic chemistry , chemistry , medicine , physics , finance , quantum mechanics , engineering , economics
The cover image shows a biofunctionalized hydrogel that is bonded directly onto myocardial tissue, delivering regenerative cells and therapeutics. On page 64 , Andrés García and co‐workers describe how maleimide‐based cross‐linking improves polyethylene glycol hydrogel engineering, leading to rapid gelation, high cytocom‐patibility, and facile in situ delivery.