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MICROFLUIDICS: Synthesis of Size‐Tunable Polymeric Nanoparticles Enabled by 3D Hydrodynamic Flow Focusing in Single‐Layer Microchannels (Adv. Mater. 12/2011)
Author(s) -
Rhee Minsoung,
Valencia Pedro M.,
Rodriguez Maria I.,
Langer Robert,
Farokhzad Omid C.,
Karnik Rohit
Publication year - 2011
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201190043
Subject(s) - materials science , microfluidics , nanoparticle , polymer , nanotechnology , flow (mathematics) , layer (electronics) , inlet , flow focusing , microchannel , composite material , mechanics , mechanical engineering , physics , engineering
Robust microfluidic synthesis of polymer nanoparticles based on nanoprecipitation is reported by Omid C. Farokhzad, Rohit Karnik, and co‐workers on p. H79 . 3D hydrodynamic flow focusing, realized by constructing three sequential inlets for vertical focusing followed by a conventional cross junction for horizontal focusing, isolates the polymer precursors from the channelwalls, both vertically and horizontally.