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Using Graphene Oxide High Near‐Infrared Absorbance for Photothermal Treatment of Alzheimer's Disease
Author(s) -
Li Meng,
Yang Xinjian,
Ren Jinsong,
Qu Konggang,
Qu Xiaogang
Publication year - 2012
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201104864
Subject(s) - photothermal therapy , graphene , materials science , absorbance , oxide , thioflavin , amyloid (mycology) , selectivity , nanotechnology , irradiation , infrared , alzheimer's disease , optics , disease , medicine , inorganic chemistry , chemistry , chromatography , organic chemistry , pathology , metallurgy , physics , nuclear physics , catalysis
A novel strategy to dissociate amyloid aggregation is presented, using localised heat generation from a clinically used amyloid staining dye, thioflavin‐S (ThS)‐modified graphene oxide (GO) under NIR laser irradiation. Compared to traditional chemotherapies, photothermal therapy shows reduced side effects and improved selectivity and safety.