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Mn 2+ Dopant‐Controlled Synthesis of NaYF 4 :Yb/Er Upconversion Nanoparticles for in vivo Imaging and Drug Delivery
Author(s) -
Tian Gan,
Gu Zhanjun,
Zhou Liangjun,
Yin Wenyan,
Liu Xiaoxiao,
Yan Liang,
Jin Shan,
Ren Wenlu,
Xing Gengmei,
Li Shoujian,
Zhao Yuliang
Publication year - 2012
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201104741
Subject(s) - materials science , photon upconversion , dopant , nanoparticle , drug delivery , doping , nanotechnology , manganese , in vivo , nuclear chemistry , optoelectronics , chemistry , metallurgy , microbiology and biotechnology , biology
Pure dark red emission (650–670nm) of NaYF 4 :Yb/Er upconversion nanoparticles (UCNPs) is achieved by manganese ions (Mn 2+ ) doping. In addition, the Mn 2+ ‐ doping can also control the crystalline phase and size of the resulting UCNPs simultaneously. Drug delivery studies suggest the promise of these UCNPs as drug carriers for intracellular drug delivery and eventually as a multifunctional nanoplatform for simultaneous diagnosis and therapy.