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A Strategy for Depositing Different Types of Cells in Three Dimensions to Mimic Tubular Structures in Tissues
Author(s) -
Yuan Bo,
Jin Yu,
Sun Yi,
Wang Dong,
Sun Jiashu,
Wang Zhuo,
Zhang Wei,
Jiang Xingyu
Publication year - 2012
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201104589
Subject(s) - materials science , nanotechnology , tube (container) , fabrication , orientation (vector space) , membrane , engineering drawing , composite material , engineering , biology , biochemistry , pathology , medicine , alternative medicine , geometry , mathematics
The fabrication of tubular structures , with multiple cell types forming different layers of the tube walls, is described using a stress‐induced rolling membrane (SIRM). Cell orientation inside the tubes can also be controlled by topographical contact guidance. These layered tubes precisely mimic blood vessels and many other tubular structures, suggesting that they may be of great use in tissue engineering.