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Direct Attachment of Microbial Organisms to Material Surfaces Through Sequence‐Specific DNA Hybridization
Author(s) -
Twite Amy A.,
Hsiao Sonny C.,
Onoe Hiroaki,
Mathies Richard A.,
Francis Matthew B.
Publication year - 2012
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201104336
Subject(s) - dna , materials science , nanotechnology , organism , microfluidics , sequence (biology) , biophysics , biology , biochemistry , genetics
A new technique is reported for the attachment of synthetic DNA strands to the surfaces of microbial organisms. This gives algal, bacterial, and fungal cells the ability to bind to complementary strands extending from patterned surfaces that can be produced on platforms such as microfluidic devices. The ability of this method to establish complex 2‐ and 3‐dimensional cocultures comprising multiple organism types is also presented.