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Quantum‐Dot‐Tagged Reduced Graphene Oxide Nanocomposites for Bright Fluorescence Bioimaging and Photothermal Therapy Monitored In Situ
Author(s) -
Hu ShangHsiu,
Chen YuWei,
Hung WenTing,
Chen IWei,
Chen SanYuan
Publication year - 2012
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201104070
Subject(s) - photothermal therapy , graphene , materials science , nanocomposite , quantum dot , fluorescence , nanotechnology , oxide , graphene quantum dot , in situ , optoelectronics , optics , chemistry , physics , organic chemistry , metallurgy
Quantum‐dot‐tagged reduced graphene oxide (QD‐rGO) nanocomposites (left) internalized into targeted tumor cells display bright fluorescence from the QDs (right); by absorbing NIR radiation incident on the rGO and converting it into heat, they also cause simultaneous cell death and fluorescence reduction (bottom). The nanocomposite is thus capable of tumor imaging, photothermal therapy and in situ monitoring of treatment in progress.