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Conjugated Polyelectrolyte‐Antibody Hybrid Materials for Highly Fluorescent Live Cell‐Imaging
Author(s) -
Lee Kangwon,
Lee Jiseok,
Jeong Eun Jeong,
Kronk Adam,
ElenitobaJohnson Kojo S. J.,
Lim Megan S.,
Kim Jinsang
Publication year - 2012
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201103895
Subject(s) - conjugated system , materials science , polyelectrolyte , fluorescence , conjugate , polymer , nanotechnology , luminescence , biophysics , optoelectronics , optics , biology , mathematical analysis , physics , mathematics , composite material
Conjugated polyelectrolyte‐antibody hybrid materials promise to enhance the utility of conjugated polymers in bioimaging field. Polymer‐antibody conjugates that are biologically safe and highly sensitive and selective to cells are designed to image human T or B lymphocytes. In the clear state, the observed efficiency of luminescence is superior to that of commercially available FITC‐antibody probe.