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Hemostatic Multilayer Coatings
Author(s) -
Shukla Anita,
Fang Jean C.,
Puranam Sravanthi,
Jensen Flemming R.,
Hammond Paula T.
Publication year - 2012
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201103794
Subject(s) - materials science , tannic acid , gelatin , hemostasis , layer (electronics) , coating , layer by layer , porosity , thrombin , nanotechnology , chemical engineering , composite material , platelet , organic chemistry , surgery , medicine , chemistry , engineering , immunology , biology
Spray layer‐by‐layer assembly is used to create hemostatic films containing thrombin and tannic acid. The spray assembly technique enables coating of porous and absorbent commercial gelatin sponges with these films. Coated sponges are able to promote instantaneous hemostasis in a porcine spleen bleeding model.