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Aptamer‐Mediated Efficient Capture and Release of T Lymphocytes on Nanostructured Surfaces
Author(s) -
Chen Li,
Liu Xueli,
Su Bin,
Li Jing,
Jiang Lei,
Han Dong,
Wang Shutao
Publication year - 2011
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201102435
Subject(s) - aptamer , materials science , nanotechnology , dna , silicon nanowires , planar , nanowire , computer science , microbiology and biotechnology , biology , computer graphics (images) , biochemistry
A nanostructured platform that combines silicon nanowire arrays and DNA aptamers realizes significant capture and efficient release of T lymphocytes. An approximately two orders of magnitude enhancement in capture efficiency compared to planar surfaces is observed with good release performance. This method of capture and release provides an artful strategy to fulfill the demands of cell isolation and diagnosis.