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A Graphene–Conjugated Oligomer Hybrid Probe for Light‐Up Sensing of Lectin and Escherichia Coli
Author(s) -
Wang Lihua,
Pu KanYi,
Li Jing,
Qi Xiaoying,
Li Hai,
Zhang Hua,
Fan Chunhai,
Liu Bin
Publication year - 2011
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201102227
Subject(s) - graphene , conjugated system , materials science , fluorescence , oligomer , nanoprobe , fluorophore , escherichia coli , concanavalin a , lectin , quenching (fluorescence) , photochemistry , nanotechnology , biophysics , biochemistry , nanoparticle , polymer chemistry , chemistry , biology , optics , polymer , physics , in vitro , composite material , gene
A water‐soluble neutral fluorescent conjugated oligomer (FBT) is integrated with graphene oxide (GO) to form a hybrid nanoprobe with extremely low fluorescence background due to the robust quenching capability of GO. The contact between GO and FBT can be effectively shielded by Concanavalin A because of the strong specific protein–carbohydrate interaction, which ultimately allows for light‐up visual detection of lectin and Escherichia coli .