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Cell‐Compatible Hydrogels: A Microfluidic Hydrogel Capable of Cell Preservation without Perfusion Culture under Cell‐Based Assay Conditions (Adv. Mater. 28/2010)
Author(s) -
Xu Yan,
Sato Kae,
Mawatari Kazuma,
Konno Tomohiro,
Jang Kihoon,
Ishihara Kazuhiko,
Kitamori Takehiko
Publication year - 2010
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201090092
Subject(s) - self healing hydrogels , microfluidics , materials science , viability assay , cell , cell culture , biomedical engineering , perfusion , biophysics , microbiology and biotechnology , nanotechnology , chemistry , biology , medicine , polymer chemistry , biochemistry , genetics
Yan Xu and co‐workers report on p. 3017 on a phospholipid polymer hydrogel that exhibits a remarkable ability to preserve cells on microfluidic chips without perfusion culture under cell‐based assay conditions, with characteristics including maintenance of high cell viability, restraint of cell proliferation, and minimization of cellular function loss over a period of days and weeks. This material could establish a revolutionary flexibility for cellbased applications.