Controlled and Sustained Release of Drugs from Dendrimer–Nanoparticle Composite Films | Zendy

Park MyoungHwan | Zendy; Agasti Sarit S. | Zendy; Creran Brian | Zendy; Kim Chaekyu | Zendy; Rotello Vincent M. | Zendy

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Controlled and Sustained Release of Drugs from Dendrimer–Nanoparticle Composite Films

Author(s) -

Park MyoungHwan,

Agasti Sarit S.,

Creran Brian,

Kim Chaekyu,

Rotello Vincent M.

Publication year - 2011

Publication title -

advanced materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.707

H-Index - 527

eISSN - 1521-4095

pISSN - 0935-9648

DOI - 10.1002/adma.201004409

Subject(s) - dendrimer , materials science , nanotechnology , composite number , drug delivery , nanoparticle , dithiocarbamate , modular design , controlled release , process (computing) , computer science , polymer chemistry , composite material , metallurgy , operating system

A dendrimer–nanoparticle hybrid scaffold based on robust dithiocarbamate formation provides a controlled drug delivery system. These composite films are non‐toxic and can incorporate a variety of guests, providing sustained drug release over multiple uses. The system is highly modular: the release process can be easily tuned by altering the dendrimer generation and the size of the AuNPs, generating a versatile delivery system.

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