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Controlled and Sustained Release of Drugs from Dendrimer–Nanoparticle Composite Films
Author(s) -
Park MyoungHwan,
Agasti Sarit S.,
Creran Brian,
Kim Chaekyu,
Rotello Vincent M.
Publication year - 2011
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201004409
Subject(s) - dendrimer , materials science , nanotechnology , composite number , drug delivery , nanoparticle , dithiocarbamate , modular design , controlled release , process (computing) , computer science , polymer chemistry , composite material , metallurgy , operating system
A dendrimer–nanoparticle hybrid scaffold based on robust dithiocarbamate formation provides a controlled drug delivery system. These composite films are non‐toxic and can incorporate a variety of guests, providing sustained drug release over multiple uses. The system is highly modular: the release process can be easily tuned by altering the dendrimer generation and the size of the AuNPs, generating a versatile delivery system.