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Metal‐Enhanced Fluorescence to Quantify Bacterial Adhesion
Author(s) -
Lee Kangwon,
Hahn Lewis D.,
Yuen William W.,
Vlamakis Hera,
Kolter Roberto,
Mooney David J.
Publication year - 2011
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201004096
Subject(s) - materials science , adhesion , fluorescence , nanoscopic scale , nanotechnology , cell adhesion , metal , fluorescence microscope , biophysics , optics , composite material , biology , metallurgy , physics
A metal‐enhanced fluorescence assay enables z ‐tracking of cell adhesion on surfaces. It is based on a significant enhancement in the fluorescence of labeled bacteria upon approaching a surface and can be used to quantitatively define cell adhesion based on the nanoscale distance between the cells and the surfaces.