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Intrafibrillar Collagen Mineralization Produced by Biomimetic Hierarchical Nanoapatite Assembly
Author(s) -
Liu Yan,
Li Nan,
Qi Yipin,
Dai Lin,
Bryan Thomas E.,
Mao Jing,
Pashley David H.,
Tay Franklin R.
Publication year - 2011
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201003882
Subject(s) - endodontics , medicine , dentistry , traumatology , oral and maxillofacial surgery , library science , medical school , medical education , surgery , computer science , orthopedic surgery
Phosphorous‐based templating analogs of extracellular matrix proteins are used as templates in conjunction with polycarboxylic acid‐stabilized amorphous calcium phosphate nanoprecursors to create a highly ordered intrafibrillar apatite crystallite assembly within a collagen fibril. The assembly recapitulates the gap and overlap arrangement of collagen molecules.