Temperature‐Responsive Polymer Brushes Switching from Bactericidal to Cell‐Repellent | Zendy

Laloyaux Xavier | Zendy; Fautré Emilie | Zendy; Blin Thomas | Zendy; Purohit Viswas | Zendy; Leprince Jérôme | Zendy; Jouenne Thierry | Zendy; Jonas Alain M. | Zendy; Glinel Karine | Zendy

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Temperature‐Responsive Polymer Brushes Switching from Bactericidal to Cell‐Repellent

Author(s) -

Laloyaux Xavier,

Fautré Emilie,

Blin Thomas,

Purohit Viswas,

Leprince Jérôme,

Jouenne Thierry,

Jonas Alain M.,

Glinel Karine

Publication year - 2010

Publication title -

advanced materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.707

H-Index - 527

eISSN - 1521-4095

pISSN - 0935-9648

DOI - 10.1002/adma.201002538

Subject(s) - materials science , polymer , nanotechnology , chemical engineering , polymer science , composite material , engineering

The composition of temperature‐responsive copolymer brushes based on oligo(ethylene glycol) methacrylates is tuned to obtain a collapse temperature of ∼35 °C. The chains are grafted by antibacterial magainin I peptide, whose activity is tested at different temperatures against various bacteria. The brushes switch from bactericidal to cell‐repellent below and slightly above 35 °C, respectively, due to the progressive vertical collapse of the brush.

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