Premium
Thermodynamic Underpinnings of Cell Alignment on Controlled Topographies
Author(s) -
Ding Yifu,
Sun Jirun,
Ro Hyun Wook,
Wang Zhen,
Zhou Jing,
Lin Nancy J.,
Cicerone Marcus T.,
Soles Christopher L.,
LinGibson Sheng
Publication year - 2011
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201001757
Subject(s) - wetting , anisotropy , materials science , surface (topology) , adhesion , nanotechnology , work (physics) , information retrieval , computer science , optics , physics , thermodynamics , composite material , geometry , mathematics
The initial stages of cell alignment in response to surface topography can be largely described in terms of the work of adhesion encountered by a classical liquid droplet during spreading on a rough surface. This is manifested through a striking correlation between degree of cell alignment and anisotropic wetting of water droplets on the same topographical surfaces.