Conjugated Oligoelectrolyte Harnessed Polyhedral Oligomeric Silsesquioxane as Light‐Up Hybrid Nanodot for Two‐Photon Fluorescence Imaging of Cellular Nucleus | Zendy

Pu KanYi | Zendy; Li Kai | Zendy; Zhang Xinhai | Zendy; Liu Bin | Zendy

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Conjugated Oligoelectrolyte Harnessed Polyhedral Oligomeric Silsesquioxane as Light‐Up Hybrid Nanodot for Two‐Photon Fluorescence Imaging of Cellular Nucleus

Author(s) -

Pu KanYi,

Li Kai,

Zhang Xinhai,

Liu Bin

Publication year - 2010

Publication title -

advanced materials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.707

H-Index - 527

eISSN - 1521-4095

pISSN - 0935-9648

DOI - 10.1002/adma.201001544

Subject(s) - silsesquioxane , nanodot , fluorescence , conjugated system , materials science , nucleus , two photon excitation microscopy , excited state , biophysics , photochemistry , nanotechnology , optics , chemistry , polymer , biology , nuclear physics , physics , microbiology and biotechnology , composite material

A water‐soluble organic/inorganic hybrid nanodot based on polyhedral oligomeric silsesquioxane (POSS) and conjugated oligoelectrolyte is designed and synthesized for two‐photon fluorescence imaging of cellular nucleus, which takes advantage of its small size (∼3.3 nm) that imparts nucleus permeability and substantial DNA‐enhanced two‐photon excited fluorescence that allows illuminating the nucleus with a high contrast.

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