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Specific Protein Detection Using Thermally Reduced Graphene Oxide Sheet Decorated with Gold Nanoparticle‐Antibody Conjugates
Author(s) -
Mao Shun,
Lu Ganhua,
Yu Kehan,
Bo Zheng,
Chen Junhong
Publication year - 2010
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.201000520
Subject(s) - graphene , materials science , nanoparticle , colloidal gold , biosensor , conjugate , oxide , nanotechnology , conjugated system , polymer , composite material , metallurgy , mathematical analysis , mathematics
A highly sensitive and selective field‐effect transistor biosensor using thermally reduced graphene oxide (TRGO) sheet decorated with gold nanoparticle‐antibody conjugates is demonstrated. Probe antibody (anti‐Immunoglobulin G) is labeled on the surface of the TRGO sheet through gold nanoparticles and electrical detection of the protein binding (Immunoglobulin G and anti‐Immunoglobulin G) is accomplished by FET and dc measurements.